![]() Computed tomography (CT) chest may be added as a key supplemental tool for the diagnosis of SARS-CoV-2 given its reported improved sensitivity relative to RT-PCR (98 vs. In symptomatic patients, chest X-rays are typically obtained. Despite its suboptimal sensitivity, nucleic acid testing (reverse transcription polymerase chain reaction ) has been regarded as the gold standard to confirm the diagnosis of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). In many patients, COVID-19 presents with nonspecific symptoms such as fever, cough, and chest pain, while in some others, the infection remains asymptomatic. The coronavirus disease 2019 (COVID-19) outbreak has infected over 131 million people and caused 2.85 million deaths worldwide, as of early April 2021. Current documented false-positive findings for 68Ga-DOTATATE PET/CT include pancreatic uncinate process activity, prostatitis, splenosis, postradiation therapy change, paraganglioma, pheochromocytoma, neuroblastoma, meningioma, and osteoblastic activity. This case highlights the importance of including COVID-19 on the differential diagnosis when radiotracer uptake appears in 68Ga-DOTATATE PET/CT.ĬOVID-19 should be included in the differential diagnosis when radiotracer uptake appears in NETSPOT 68Ga-DOTATATE PET/CT. With the rise of worldwide COVID-19 cases, and the continued use of NETSPOT for somatostatin avid neoplasms, it is imperative that diagnostic measures of this disease are clearly understood. Radiotracer uptake corresponding to the anatomic infiltrates was also seen in the bilateral pneumonia. Current maximal intensity project image from 68Ga-DOTATATE PET/CT demonstrated numerous hypermetabolic foci in the upper abdominal lymph nodes, consistent with somatostatin-avid pancreatic islet cell neoplasm. ![]() Here, we report a rare case of incidental coronavirus disease 2019 (COVID-19) detection using 68Ga-DOTATATE PET/CT for a 48-year-old patient with COVID-19 who presented to our nuclear medicine department for oncologic and neuroendocrine indications. ![]() In the detection and characterization of neuroendocrine tumors (NETs), the NETSPOT 68Ga-DOTATATE positron emission tomography/computed tomography (PET/CT) utilizes a somatostatin analog to capture whole body imaging of somatostatin receptors.
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